HEBP1 — Heme binding protein 1
HEBP1 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
HEBP1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Enterocytes | Gluconeogenesis/fructose metabolism Nutrient metabolism | AADAC, ADIRF, ENTPD5, FBP1, KHK, PCK2, PEPD, PGRMC2 +2 more | View in SCUBA |
| Lymphatic endothelial | GIMAP mediated permeability Mitochondrial & OxPhos | AGTRAP, CCNI, GIMAP1, GIMAP4, GIMAP7, GPR146, LYL1, PSMB9 +2 more | View in SCUBA |
About the gene
| Synonyms | HBP, HEBP |
|---|---|
| Chromosome | 12: 12974870-13000265 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
May bind free porphyrinogens that may be present in the cell and thus facilitate removal of these potentially toxic compound. Binds with a high affinity to one molecule of heme or porphyrins. It binds metalloporphyrins, free porphyrins and N-methylprotoporphyrin with similar affinities
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.