SLC6A20 — Solute carrier family 6 member 20
SLC6A20 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SLC6A20's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Enterocytes | Apical Na+/H+ transport Absorption | COL17A1, CTSA, GNG12, LHFPL2, MICAL2, PLS1, SLC9A3 | View in SCUBA |
About the gene
| Synonyms | IMINO, SIT1, XT3, Xtrp3 |
|---|---|
| Chromosome | 3: 45755449-45796574 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters |
| Biological process | Amino-acid transport, Symport, Transport |
Function
Mediates the Na(+)- and Cl(-)-dependent uptake of imino acids such as L-proline, N-methyl-L-proline and pipecolate as well as N- methylated amino acids. Also transports glycine, regulates proline and glycine homeostasis in the brain playing a role in the modulation of NMDAR currents.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.