TCL1A — TCL1 family AKT coactivator A
TCL1A belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TCL1A's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | Naive B-cell identity B cell maturation | ALOX5AP, CD79B, HLA-DOB, IRF8, NCF1, P2RX5, PLEKHF2, SEC62 +7 more | View in SCUBA |
About the gene
| Synonyms | TCL1 |
|---|---|
| Chromosome | 14: 95709947-95714196 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Cancer-related genes, Disease related genes, Predicted intracellular proteins |
Function
Enhances the phosphorylation and activation of AKT1, AKT2 and AKT3. Promotes nuclear translocation of AKT1. Enhances cell proliferation, stabilizes mitochondrial membrane potential and promotes cell survival.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.