TUBGCP3 — Tubulin gamma complex associated protein 3
TUBGCP3 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TUBGCP3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Macrophages | Centrosome & DNA Repair Cell cycle | ANKRD13A, BRCA2, CASP2, CBX5, CCDC14, CEP152, CEP78, CKAP5 +34 more | View in SCUBA |
About the gene
| Synonyms | GCP3, SPBC98, Spc98p |
|---|---|
| Chromosome | 13: 112485011-112588205 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Predicted intracellular proteins |
Function
Component of the gamma-tubulin ring complex (gTuRC) which mediates microtubule nucleation. The gTuRC regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments, a critical step in centrosome duplication and spindle formation.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.