CCDC14 — Coiled-coil domain containing 14
CCDC14 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CCDC14's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Post-transcriptional regulation RNA processing | BCL11B, CHD2, CHD6, CREBZF, DDX39B, DNASE1, EVI2B, FAM78A +21 more | View in SCUBA |
| Gamma-delta T cells | mRNA Splicing RNA processing & translation | ACTB, ACTG1, ACTL6A, ACTR3, AK2, BRD8, CASP2, CCT5 +13 more | |
| Macrophages | Centrosome & DNA Repair Cell cycle | ANKRD13A, BRCA2, CASP2, CBX5, CEP152, CEP78, CKAP5, CSE1L +34 more | View in SCUBA |
About the gene
| Synonyms | DKFZp434L1050, FLJ12892 |
|---|---|
| Chromosome | 3: 123897305-123961408 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
Negatively regulates centriole duplication. Negatively regulates CEP63 and CDK2 centrosomal localization
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.