ZNF593 — Zinc finger protein 593
ZNF593 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ZNF593's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Nucleotide biosynthesis Housekeeping | CCT7, COPRS, DCTPP1, MRPL12, MRPL4, NHP2, NME1, PPA1 +6 more | View in SCUBA |
| Macrophages | Mitochondrial Biogenesis Mitochondrial & OxPhos | AIMP1, ATP5F1D, ATP5MC1, C1QBP, CCT2, CCT3, CCT7, CHCHD1 +38 more | View in SCUBA |
About the gene
| Synonyms | ZT86 |
|---|---|
| Chromosome | 1: 26169908-26170873 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Predicted intracellular proteins |
| Molecular function | DNA-binding |
| Biological process | Ribosome biogenesis, Transcription, Transcription regulation |
Function
Involved in pre-60S ribosomal particles maturation by promoting the nuclear export of the 60S ribosome. Negatively modulates the DNA binding activity of Oct-2 and therefore its transcriptional regulatory activity
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.