BAIAP3/CHCHD6 immature axis
Gene co-expression module in Enteroendocrine cells
| Category | EEC development |
|---|---|
| Genes | 0 |
| Annotation certainty | 2 of 5 |
| Annotation consistency | 4 of 13 genes have a known function matching the annotation |
Why this annotation
No subset reaches 3x and the genes lack a shared pathway. However, the module correlates strongly with PAX4/NKX2-2 specification (0.73) and the other progenitor modules, and shows a mild pre_EEC bias of mitochondrial/biosynthetic genes (CHCHD6, TOMM40, AIMP2) plus the dense-core-vesicle gene BAIAP3. That points to a weak immaturity-associated axis rather than contamination.
Genes
Most correlated modules
- ELAVL4 post-transcriptional axis · correlation 0.61
- Ciliary axoneme genes · correlation 0.58
- LGR5/NUMBL immature state · correlation 0.56
- PAX4/NKX2-2 specification · correlation 0.49
- Crypt-positioned EEC state · correlation 0.44
- Synaptic adhesion genes · correlation 0.42
- ELR+ chemokine secretion · correlation 0.35
Module annotations were drafted by a large language model from the module's genes, then reviewed and approved by a domain expert. See sources & licences.