Ciliary axoneme genes
Gene co-expression module in Enteroendocrine cells
| Category | Cytoskeletal |
|---|---|
| Genes | 0 |
| Annotation certainty | 3 of 5 |
| Annotation consistency | 8 of 18 genes have a known function matching the annotation |
Why this annotation
Axonemal dynein heavy chains (DNAH6/7/12), CFAP69/91/92, RSPH4A and FHAD1 form a cilium/axoneme program co-enriched at modest folds across peptidergic D, K and L cells, making it a shared peptidergic ciliary state broader than L-cell Ciliary Genes.
Genes
Most correlated modules
- L/D-cell excitability genes · correlation 0.74
- L-cell Accessory Program · correlation 0.72
- L-cell receptor/adhesion program · correlation 0.68
- Peptidergic branch genes · correlation 0.66
- L-cell Ciliary Genes · correlation 0.65
- D/L-cell lineage signature · correlation 0.64
- Beta-cell-like glucose sensing · correlation 0.60
- BAIAP3/CHCHD6 immature axis · correlation 0.58
Module annotations were drafted by a large language model from the module's genes, then reviewed and approved by a domain expert. See sources & licences.