Granule transport
Gene co-expression module in Paneth cells
| Category | Secretion |
|---|---|
| Genes | 0 |
| Annotation certainty | 1 of 5 |
| Annotation consistency | 3 of 7 genes have a known function matching the annotation |
Why this annotation
This is a mixed small module. MYO5C mediates secretory granule transport in exocrine epithelia, and WDFY2 is endosomal. CCL24 (eotaxin-2) is a chemokine, and BACH1 and ELF2 are transcription factors. SNTB1 and SLC36A4 are peripheral. A secretory or endosomal trafficking theme is weakly supported, possibly alongside chemokine output.
Genes
Most correlated modules
- Rho GTPase regulation · correlation 0.85
- Chromatin remodeling regulators · correlation 0.82
- Long-gene nuclear transcripts · correlation 0.76
- Vesicle trafficking · correlation 0.58
- Crypt progenitor program · correlation 0.53
- Chromatin remodeling · correlation 0.52
- Long-gene nuclear transcripts · correlation 0.35
Module annotations were drafted by a large language model from the module's genes, then reviewed and approved by a domain expert. See sources & licences.