Generic gene-expression machinery
Gene co-expression module in Monocytes
| Category | Housekeeping |
|---|---|
| Genes | 0 |
| Annotation certainty | 2 of 5 |
| Annotation consistency | 6 of 13 genes have a known function matching the annotation |
Why this annotation
This is a small module of ubiquitous genes with no shared program. It covers RNA binding (LARP4, FUS), nuclear pore (NUP93), Mediator (MED27), polyamine synthesis (AMD1) and cAMP signaling (ADCY7). Expression is uniform, consistent with a generic housekeeping or detection-depth covariation shared with its neighbors.
Genes
Most correlated modules
- Generic transcriptional housekeeping · correlation 0.92
- Mitochondrial translation/metabolism · correlation 0.91
- mRNA processing/export · correlation 0.88
- Small GTPase signaling · correlation 0.86
- Basal endolysosomal maintenance · correlation 0.85
- Biosynthetic/mitochondrial housekeeping · correlation 0.85
- ER protein quality control · correlation 0.85
- RNA Processing/Translation · correlation 0.85
Module annotations were drafted by a large language model from the module's genes, then reviewed and approved by a domain expert. See sources & licences.