ATP Synthase Complex
Gene co-expression module in Plasmacytoid dendritic cells
| Category | Mitochondrial & OxPhos |
|---|---|
| Genes | 0 |
| Annotation certainty | 4 of 5 |
| Annotation consistency | 17 of 20 genes have a known function matching the annotation |
Why this annotation
This module is almost entirely composed of ATP synthase (Complex V) subunits: ATP5PF, ATP5MF, ATP5MG, ATP5MC2, ATP5MC3, ATP5ME, ATP5MJ, ATP5F1D, ATP5MK, ATP5IF1, ATP5MC1, ATP5F1E, ATP5PD, ATP5PO — covering both the F0 membrane and F1 catalytic subunits. UQCR10 is Complex III, SMDT1 regulates the mitochondrial calcium uniporter, and CHCHD10 is a mitochondrial intermembrane space protein. This is the most coherent module in the batch, representing ATP synthase/Complex V.
Genes
Most correlated modules
- ATP Synthase F1 · correlation 0.89
- Complex I Subunits · correlation 0.75
- Respiratory Chain · correlation 0.75
- Complex I Assembly · correlation 0.74
Module annotations were drafted by a large language model from the module's genes, then reviewed and approved by a domain expert. See sources & licences.