ATP Synthase F1
Gene co-expression module in Plasmacytoid dendritic cells
| Category | Mitochondrial & OxPhos |
|---|---|
| Genes | 0 |
| Annotation certainty | 2 of 5 |
| Annotation consistency | 4 of 20 genes have a known function matching the annotation |
Why this annotation
This module contains ATP5F1A, ATP5F1C, ATP5F1B (ATP synthase F1 alpha, beta, gamma subunits — core catalytic components of Complex V), TOMM22 (mitochondrial import receptor), and CCT8 (chaperonin TRiC/CCT). Additional genes include translation initiation factors (EIF3D, EIF3L), chromatin regulators (XRCC6/Ku70, SMARCB1, HMGN1), RAC2 (GTPase), and SOD1 (antioxidant). The module is mixed housekeeping with a notable ATP synthase F1 sub-theme, neighboring the pure ATP synthase module M67.
Genes
Most correlated modules
- ATP Synthase Complex · correlation 0.89
Module annotations were drafted by a large language model from the module's genes, then reviewed and approved by a domain expert. See sources & licences.