ACTR1A — Actin related protein 1A
ACTR1A belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ACTR1A's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Glycosylation & trafficking Protein processing & ER | AASDHPPT, ABHD12, ANKRD35, AP1S1, ARRDC1, ATF6B, ATG5, CDK19 +25 more | View in SCUBA |
| Gamma-delta T cells | Antiviral ISG Response Inflammation | ATRX, CD164, CYTH4, FGD3, GIT2, LASP1, PARP10, RGS3 +6 more | |
| Macrophages | ER Protein Processing Housekeeping | ANXA7, ATP6AP1, ATP6AP2, ATP6V0B, ATP6V0E1, AUP1, BCAP31, BSG +41 more | View in SCUBA |
About the gene
| Synonyms | ARP1, Arp1A |
|---|---|
| Chromosome | 10: 102461881-102502712 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Plasma proteins, Predicted intracellular proteins |
Function
Part of the ACTR1A/ACTB filament around which the dynactin complex is built. The dynactin multiprotein complex activates the molecular motor dynein for ultra-processive transport along microtubules
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.