ANKRD13D — Ankyrin repeat domain 13D
ANKRD13D belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ANKRD13D's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | GIMAP survival Immune regulation | ABLIM1, AKT3, ARL4C, C16orf54, CA5B, COPA, CRBN, DYNLT1 +16 more | View in SCUBA |
| Gamma-delta T cells | Mitochondrial Biogenesis Mitochondrial & OxPhos | ATP5ME, ATP5MJ, CAMTA1, CD2, CTDNEP1, DPP7, EIF3D, FBL +11 more | |
| Macrophages | Pre-mRNA Splicing Housekeeping | AAK1, ANKRD12, ARGLU1, BRD2, C3orf62, CREBZF, DMTF1, FAM133B +20 more | View in SCUBA |
About the gene
| Chromosome | 11: 67289300-67302485 |
|---|---|
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.