ANKRD12 — Ankyrin repeat domain 12
ANKRD12 belongs to a gene co-expression module in 7 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ANKRD12's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | Chromatin Regulation DNA/chromatin regulation | AKAP9, BBX, CHD2, CHD7, IRF1, KDM7A, L3MBTL3, MAP3K1 +8 more | View in SCUBA |
| Enterocytes | Long-gene nuclear transcripts Technical artifact | CEMIP2, EPS8, ETNK1, GCC2, MYO1E, SLC2A13, TCF7L2 | View in SCUBA |
| Gamma-delta T cells | Stress Negative Feedback Immune regulation | AZIN1, CCDC186, CDKN1A, CYLD, DENND4A, DNAJB6, DUSP10, ELL +7 more | |
| Glial cells | Cytoskeletal Glial Homeostasis Cytoskeletal | ABCA1, ATP1B1, FERMT2, PHLDB1, PRKCA, TUBA1A, TUBA1B, TUBB2B +1 more | View in SCUBA |
| Innate lymphoid cells | Golgi RNA Processing RNA processing & translation | ATM, DDX17, GCC2, GOLGA4, LUC7L3, MIER1, MLEC, MYCBP2 +11 more | View in SCUBA |
| Macrophages | Pre-mRNA Splicing Housekeeping | AAK1, ANKRD13D, ARGLU1, BRD2, C3orf62, CREBZF, DMTF1, FAM133B +20 more | View in SCUBA |
| Mucosal-associated invariant T cell | Circadian Transcriptional Regulation DNA/chromatin regulation | ABCB1, ATOSA, BMAL1, CEP250, GCC2, MIA3, MIER1, NCOA7 +2 more |
About the gene
| Synonyms | ANCO-2, FLJ20053, GAC-1, KIAA0874 |
|---|---|
| Chromosome | 18: 9136228-9285985 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Cancer-related genes, Predicted intracellular proteins |
Function
May recruit HDACs to the p160 coactivators/nuclear receptor complex to inhibit ligand-dependent transactivation
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.