ARL8A — ADP ribosylation factor like GTPase 8A
ARL8A belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ARL8A's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | TCR Vesicular Trafficking TCR Signaling | ARL2BP, ARRDC1, C18orf32, CCDC92, CD3D, CD3G, CD99, FKBP8 +14 more | |
| Macrophages | Autophagy Lysosomal Regulation Lysosomal & pahgocytosis | ADIPOR1, ATOSB, BCL10, BROX, CCR1, CEBPB, CHMP2B, CHP1 +22 more | View in SCUBA |
About the gene
| Synonyms | ARL10B, FLJ45195, Gie2 |
|---|---|
| Chromosome | 1: 202133404-202144743 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Biological process | Cell cycle, Cell division, Chromosome partition, Mitosis, Protein transport, Transport |
Function
Plays a role in lysosome motility (By similarity). In neurons, mediates the anterograde axonal long-range transport of presynaptic lysosome-related vesicles required for presynaptic biogenesis and synaptic function (By similarity). May play a role in chromosome segregation (By similarity).
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.