ARL2BP — ADP ribosylation factor like GTPase 2 binding protein
ARL2BP belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ARL2BP's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | IL-13/STAT6 Signaling Inflammation | ABLIM1, ASRGL1, ATP8B1, BMP1, BMPR2, CLIP1, CMIP, EHBP1L1 +18 more | View in SCUBA |
| Gamma-delta T cells | TCR Vesicular Trafficking TCR Signaling | ARL8A, ARRDC1, C18orf32, CCDC92, CD3D, CD3G, CD99, FKBP8 +14 more | |
| Innate lymphoid cells | ILC1 Inflammatory Activation Inflammation | ABHD15, ALDOC, C20orf204, CCL20, CPNE7, EIPR1, ERG28, ERGIC2 +21 more | View in SCUBA |
| Macrophages | Glycogen Metabolism Housekeeping | BTF3L4, CAPN1, CD47, CRLS1, DCTD, DSTN, GLOD4, GPR65 +24 more | View in SCUBA |
About the gene
| Synonyms | BART, BART1, RP66 |
|---|---|
| Chromosome | 16: 57245259-57253635 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted intracellular proteins |
Function
Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.