ARPP21 — CAMP regulated phosphoprotein 21
ARPP21 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ARPP21's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Hematopoietic progenitor cells | Pro-B Progenitor Lymphcyte development | CD79A, CD79B, CYGB, DNTT, EBF1, FRMD4A, IL2RA, IL7R +4 more |
About the gene
| Synonyms | ARPP-21, R3HDM3, TARPP |
|---|---|
| Chromosome | 3: 35638945-35794496 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | Calmodulin-binding |
Function
Isoform 2 may act as a competitive inhibitor of calmodulin- dependent enzymes such as calcineurin in neurons
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.