BPGM — Bisphosphoglycerate mutase
BPGM belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
BPGM's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Natural Killer cells | NK Cytotoxic Activation Cytotoxicity | ABI3, ALOX5AP, ARHGDIB, CD247, GNPTAB, GZMA, HCLS1, LAT2 +3 more | View in SCUBA |
About the gene
| Chromosome | 7: 134646811-134679816 |
|---|---|
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins |
| Molecular function | Hydrolase, Isomerase |
| Biological process | Glycolysis |
Function
Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3- bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.11) activity
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.