CDCP1 — CUB domain containing protein 1
CDCP1 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CDCP1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | Thrombin Receptor Signaling Inflammatory | ADAMTS9, AGT, CDH13, EFCC1, EPS8, F2R, F2RL2, FAM89A +10 more | View in SCUBA |
| Monocytes | Monocyte Tissue Infiltration Migration & adhesion | CD59, FPR3, NRP1, NRP2, PDE4DIP, PLAU, PMP22, PTMS +3 more | View in SCUBA |
About the gene
| Synonyms | CD318, SIMA135 |
|---|---|
| Chromosome | 3: 45082277-45146422 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | CD markers, Predicted intracellular proteins, Predicted membrane proteins |
Function
May be involved in cell adhesion and cell matrix association. May play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor progression and metastasis.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.