ANXA11 — Annexin A11
ANXA11 belongs to a gene co-expression module in 7 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ANXA11's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD8⁺ T cells | Actin Cytoskeleton Dynamics Cytoskeletal | ACTG1, ACTR3, ARPC2, CAP1, CDK2AP2, RAC2, RNF181 | View in SCUBA |
| Endothelial | Arterial EC Identity Endothelial cell development | ACVRL1, ATP13A2, ENG, HPCAL1, HYAL1, LDB2, MACF1, NFIB +7 more | View in SCUBA |
| Goblet cells | Mucosal Antibacterial Defense Immune function | B3GNT7, C15orf48, C19orf33, CLIC1, CSTB, CYSTM1, ELOB, LGALS3 +8 more | View in SCUBA |
| Innate lymphoid cells | Mixed Proteostasis Metabolism Metabolism | ADRM1, ATP6V0B, CISD2, COX17, DNAJC8, DR1, EIF3I, HPRT1 +18 more | View in SCUBA |
| Mucosal-associated invariant T cell | Cytotoxic Lymphocyte Program cytotoxicity | CDKN2D, CYB5A, EMP3, ETHE1, FLT3LG, GLIPR2, LDHB, LTB +9 more | |
| Natural Killer cells | Resident NK cells Gut residency | APBB1IP, CD151, CXXC5, HMOX2, LSP1, MPG, PPDPF, SH3BP1 +4 more | View in SCUBA |
| Smooth muscle cells | Post-translational regulators Housekeeping | BAG1, BANF1, CALM3, CAMTA1, ERH, HMGN3, MYO1C, NENF +6 more | View in SCUBA |
About the gene
| Synonyms | ANX11 |
|---|---|
| Chromosome | 10: 80150889-80205572 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters |
| Biological process | Cell cycle, Cell division |
Function
Binds specifically to calcyclin in a calcium-dependent manner (By similarity). Required for midbody formation and completion of the terminal phase of cytokinesis.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.