CDKN2B — Cyclin dependent kinase inhibitor 2B
CDKN2B belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CDKN2B's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Enterocytes | Villus-tip enterocyte transport Absorption | ABCG2, AQP3, AQP7, BEND7, C2orf88, MEP1A, MEP1B | View in SCUBA |
About the gene
| Synonyms | CDK4I, INK4B, MTS2, P15, p15INK4b, TP15 |
|---|---|
| Chromosome | 9: 22002903-22009305 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Human disease related genes, Predicted intracellular proteins |
| Biological process | Cell cycle |
Function
Interacts strongly with CDK4 and CDK6. Potent inhibitor. Potential effector of TGF-beta induced cell cycle arrest
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.