FAT1 — FAT atypical cadherin 1
FAT1 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
FAT1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Enterocytes | PPARA/FXR fatty acid oxidation Lipid metabolism | ALDH18A1, ANO10, CPT1A, DGKD, FMO5, NDRG1, NR1H4, PPARA +4 more | View in SCUBA |
| Smooth muscle cells | Actin Cytoskeletal Scaffold Cytoskeletal | ACTN4, ATP2B4, ATRX, DDX5, DLGAP4, EIF4G2, GNAI2, JAK1 +13 more | View in SCUBA |
About the gene
| Synonyms | CDHF7, CDHR8, FAT |
|---|---|
| Chromosome | 4: 186587794-186726722 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins |
| Biological process | Cell adhesion |
Function
Plays an essential role for cellular polarization, directed cell migration and modulating cell-cell contact
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.