DSCC1 — DNA replication and sister chromatid cohesion 1
DSCC1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
DSCC1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD8⁺ T cells | S-phase Progression Cell cycle | CENPH, CENPM, CENPU, DNAJC9, EBP, NCAPH2, PCLAF, RRM1 +5 more | View in SCUBA |
About the gene
| Synonyms | DCC1, hDCC1, MGC5528 |
|---|---|
| Chromosome | 8: 119833976-119855894 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | DNA-binding |
| Biological process | Cell cycle, DNA replication |
Function
Loads PCNA onto primed templates regulating velocity, spacing and restart activity of replication forks. May couple DNA replication to sister chromatid cohesion through regulation of the acetylation of the cohesin subunit SMC3.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.