FREM1 — FRAS1 related extracellular matrix 1
FREM1 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
FREM1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Enterocytes | Long-gene nuclear transcripts Technical artifact | ACSS2, CACNA1D, GGT6, NAALADL2, PHYHIPL, PSD3, SPON1, SUCLG2 +3 more | View in SCUBA |
| Fibroblasts | TGF-beta Response ECM remodeling | C1orf21, CBR3, CNRIP1, DOK5, GUSB, HTRA1, LRRN4CL, NR3C1 +7 more | View in SCUBA |
| Hematopoietic progenitor cells | HSC Stemness Program Stemness | ADRA2A, ALDH1A1, ATP6V0A2, CPPED1, DEPTOR, FCER1A, PBX1, PGAP4 +4 more |
About the gene
| Synonyms | C9orf143, C9orf145, C9orf154, DKFZp686M16108, FLJ25461, TILRR |
|---|---|
| Chromosome | 9: 14737152-14910995 |
| Predicted location | Intracellular, Secreted |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins |
| Molecular function | Developmental protein |
| Biological process | Cell adhesion |
Function
Extracellular matrix protein that plays a role in epidermal differentiation and is required for epidermal adhesion during embryonic development
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.