BTAF1 — B-TFIID TATA-box binding protein associated factor 1
BTAF1 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
BTAF1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Transcription-RNA Coupling DNA/chromatin regulation | AKNA, AP1G1, BZW1, CRNKL1, DDX6, DNTTIP2, DYNC1H1, EDRF1 +26 more | |
| Macrophages | Ubiquitin Proteasome Regulation Housekeeping | ARIH1, CLASP2, DENND4A, DYRK1A, FBXO11, FBXW7, GATAD2B, LMBR1 +8 more | View in SCUBA |
| Mucosal-associated invariant T cell | Transcription Factor Activity DNA/chromatin regulation | AKAP17A, HNRNPH1, HSPA9, IKZF5, LCOR, NDEL1, POLR2M, SDE2 +3 more |
About the gene
| Synonyms | MOT1, TAF-172, TAF(II)170, TAF172, TAFII170 |
|---|---|
| Chromosome | 10: 91923770-92031437 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Plasma proteins, Predicted intracellular proteins |
| Molecular function | DNA-binding, Helicase, Hydrolase |
Function
Regulates transcription in association with TATA binding protein (TBP). Removes TBP from the TATA box in an ATP-dependent manner
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.