ITIH3 — Inter-alpha-trypsin inhibitor heavy chain 3
ITIH3 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ITIH3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | ICC niche interactaion Gut motility | ABCC9, ADGRF5, ANO1, CD36, CFHR1, ESAM, FHL5, HOPX +10 more | View in SCUBA |
| Smooth muscle cells | FOXC-PRDM16 Program Development | ARHGEF10L, CARNS1, CKMT2, CMKLR1, DUSP26, FOXC1, FOXC2, MYO1D +4 more | View in SCUBA |
About the gene
| Synonyms | H3P |
|---|---|
| Chromosome | 3: 52794768-52808799 |
| Predicted location | Secreted |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted secreted proteins |
| Molecular function | Protease inhibitor, Serine protease inhibitor |
Function
May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.