ESAM — Endothelial cell adhesion molecule
ESAM belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ESAM's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Endothelial Angiogenic Identity Endothelial cell development | ACTN4, ADGRL4, APBB2, CAVIN1, CD93, CLEC14A, CLIC4, MYH9 +5 more | View in SCUBA |
| Fibroblasts | ICC niche interactaion Gut motility | ABCC9, ADGRF5, ANO1, CD36, CFHR1, FHL5, HOPX, HRH2 +10 more | View in SCUBA |
| Lymphatic endothelial | AhR mRNA Regulation RNA processing & translation | CYP1B1, DHRS3, HNRNPDL, HNRNPH1, LIF, SDC4, TIPARP, TPBG +3 more | View in SCUBA |
| Pericytes | Vascular Junction Adhesion Migration & adhesion | ABHD17A, CCDC85B, CDC37, FYN, HECW2, PREX1, SELENON, SLC44A2 +2 more | View in SCUBA |
| Smooth muscle cells | Arteriolar Mural Cells Development | FOXS1, GJA4, LINGO1, NDUFA4L2, NGF, OR51E1, OR51E2, PDGFA +3 more | View in SCUBA |
About the gene
| Synonyms | W117m |
|---|---|
| Chromosome | 11: 124752583-124762290 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted membrane proteins |
| Biological process | Cell adhesion |
Function
Can mediate aggregation most likely through a homophilic molecular interaction
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.