MYO1D — Myosin ID
MYO1D belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
MYO1D's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Macrophages | Transcriptional Kinase Regulation Housekeeping | BNC2, CABLES1, CACNB4, CDK8, ENOX2, FAF1, FOXO1, INPP4B +17 more | View in SCUBA |
| Smooth muscle cells | FOXC-PRDM16 Program Development | ARHGEF10L, CARNS1, CKMT2, CMKLR1, DUSP26, FOXC1, FOXC2, ITIH3 +4 more | View in SCUBA |
About the gene
| Synonyms | KIAA0727, myr4, PPP1R108 |
|---|---|
| Chromosome | 17: 32492522-32877177 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted intracellular proteins |
| Molecular function | Actin-binding, Calmodulin-binding, Motor protein, Myosin |
| Biological process | Protein transport, Transport |
Function
Unconventional myosin that functions as actin-based motor protein with ATPase activity (By similarity). Plays a role in endosomal protein trafficking, and especially in the transfer of cargo proteins from early to recycling endosomes (By similarity). Required for normal planar cell polarity in ciliated tracheal cells, for normal rotational polarity of cilia, and for coordinated, unidirectional ciliary movement in the trachea. Required for normal, polarized cilia organization in brain ependymal epithelial cells (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.