KIFAP3 — Kinesin associated protein 3
KIFAP3 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
KIFAP3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | CD4 Lineage Identity T cell development | ACAA1, AGPAT3, ASCC3, ATF2, KXD1, NEK7, PARP4, PPM1A +6 more | View in SCUBA |
| Hematopoietic progenitor cells | Oxidative Stress Survival Stress | GMPR, PIM1, RIPOR3, SH3BGRL, SOD2, STON2, TAFA2 |
About the gene
| Synonyms | FLA3, KAP-1, KAP3, SMAP |
|---|---|
| Chromosome | 1: 169921326-170085208 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted intracellular proteins |
Function
Involved in tethering the chromosomes to the spindle pole and in chromosome movement. Binds to the tail domain of the KIF3A/KIF3B heterodimer to form a heterotrimeric KIF3 complex and may regulate the membrane binding of this complex (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.