STON2 — Stonin 2
STON2 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
STON2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Hematopoietic progenitor cells | Oxidative Stress Survival Stress | GMPR, KIFAP3, PIM1, RIPOR3, SH3BGRL, SOD2, TAFA2 | |
| Lymphatic endothelial | Lymphatic Valve Development Valve formation | GPM6A, LRP5, MEF2C, MPP7, NFIA, NFIB, PGM5, PRKAR1B +5 more | View in SCUBA |
| Macrophages | Myeloid Signaling Regulation Innate immunity | ADGRG6, AOAH, CCDC170, CD302, CMKLR1, CPED1, DIPK2A, FAM13A +38 more | View in SCUBA |
About the gene
| Synonyms | STN2, STNB2 |
|---|---|
| Chromosome | 14: 81260652-81436465 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted intracellular proteins |
| Biological process | Endocytosis |
Function
Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.