KRT8 — Keratin 8
KRT8 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
KRT8's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Inflammatory ECM Remodeling ECM remodeling | CNTNAP3B, CYB5RL, FOXO1, IL7, ITSN1, KIF3C, LRCH2, MMP16 +6 more | View in SCUBA |
| Enterocytes | Abundant Transcript Baseline Housekeeping | ATP5IF1, C15orf48, CALM2, CHCHD2, CSTB, GHITM, LGALS3, MPC2 +6 more | View in SCUBA |
About the gene
| Synonyms | CARD2, CK-8, CK8, CYK8, K2C8, K8, KO |
|---|---|
| Chromosome | 12: 52897187-52949954 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins |
| Biological process | Host-virus interaction |
Function
Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.