LSM1 — LSM1 homolog, mRNA degradation associated
LSM1 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
LSM1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | mRNA Processing RNA processing | ABI1, AGFG1, CCND3, CD164, CHMP2B, DBF4, GHITM, HNRNPL +9 more | View in SCUBA |
| Endothelial | Actin Vesicle Trafficking Cytoskeletal | ABRACL, ACTR3, ADRM1, ANKRD9, C3orf14, CISD2, CLIC1, EIF2S1 +10 more | View in SCUBA |
| Macrophages | Mitochondrial Housekeeping Mitochondrial & OxPhos | BLOC1S2, BUD31, C14orf119, CCT5, CDC26, DGUOK, EIF2S1, GADD45GIP1 +11 more | View in SCUBA |
About the gene
| Synonyms | CASM, YJL124C |
|---|---|
| Chromosome | 8: 38163335-38176730 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | Ribonucleoprotein, RNA-binding |
| Biological process | mRNA processing, mRNA splicing |
Function
Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.