BUD31 — BUD31 homolog
BUD31 belongs to a gene co-expression module in 6 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
BUD31's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | RNA processing splicing RNA processing | DNAJC8, EDF1, EIF2S1, GTF3C6, HPRT1, ILF2, LAMTOR5, MIIP +11 more | View in SCUBA |
| CD8⁺ T cells | Rho GTPase Cytoskeletal Cytoskeletal | ARHGDIA, CYB5B, MORF4L1, PIN1, POLR2G, PPP4C, PSMB7, RAC1 +5 more | View in SCUBA |
| Gamma-delta T cells | Anabolic Activation Response Housekeeping | ABHD5, ATF4, ATP6V0C, ATP6V1G1, BCL7B, CALM2, CHRAC1, DYNLL2 +26 more | |
| Innate lymphoid cells | mRNA Stability & Splicing RNA processing & translation | EIF4G2, GNAI3, HSPA9, PABPC1, PABPC4, PAIP2, PAPOLA, PRKAR1A +6 more | View in SCUBA |
| Macrophages | Mitochondrial Housekeeping Mitochondrial & OxPhos | BLOC1S2, C14orf119, CCT5, CDC26, DGUOK, EIF2S1, GADD45GIP1, LSM1 +11 more | View in SCUBA |
| Mucosal-associated invariant T cell | BMP/TGF-β Inhibitory Immune regulation | ACHE, FAM43A, ID1, LMNA, N4BP3, PRR7, RGS16, SMAD7 +2 more |
About the gene
| Synonyms | Cwc14, EDG-2, EDG2, fSAP17, G10, YCR063W |
|---|---|
| Chromosome | 7: 99408641-99419616 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Predicted intracellular proteins |
| Biological process | mRNA processing, mRNA splicing, Transcription, Transcription regulation |
Function
Involved in the pre-mRNA splicing process. May play a role as regulator of AR transcriptional activity; may increase AR transcriptional activity.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.