MIIP — Migration and invasion inhibitory protein
MIIP belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
MIIP's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | RNA processing splicing RNA processing | BUD31, DNAJC8, EDF1, EIF2S1, GTF3C6, HPRT1, ILF2, LAMTOR5 +11 more | View in SCUBA |
About the gene
| Synonyms | FLJ12438, IIp45 |
|---|---|
| Chromosome | 1: 12019466-12032045 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
Inhibits glioma cells invasion and down-regulates adhesion- and motility-associated genes such as NFKB2 and ICAM1. Exhibits opposing effects to IGFBP2 on cell invasion
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.