PCP4 — Purkinje cell protein 4
PCP4 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PCP4's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | ICC neuromuscular junction Gut motility | ATP1A2, ATRNL1, CASQ2, COL19A1, CTNNA3, FAM83D, KCNIP4, LRRC7 +6 more | View in SCUBA |
| Smooth muscle cells | SMC Ion Signaling Contractility | ANTXR2, ATP1B1, CDKN1C, CENPW, FAM83D, FXYD6, GAS1, KCNMA1 +12 more | View in SCUBA |
About the gene
| Synonyms | PEP-19 |
|---|---|
| Chromosome | 21: 39867438-39929397 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | Calmodulin-binding |
Function
Functions as a modulator of calcium-binding by calmodulin. Thereby, regulates calmodulin activity and the different processes it controls. For instance, may play a role in neuronal differentiation through activation of calmodulin-dependent kinase signaling pathways.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.