ATP1A2 — ATPase Na+/K+ transporting subunit alpha 2
ATP1A2 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ATP1A2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | ICC neuromuscular junction Gut motility | ATRNL1, CASQ2, COL19A1, CTNNA3, FAM83D, KCNIP4, LRRC7, MAPK4 +6 more | View in SCUBA |
| Glial cells | Glial Synaptic Adhesion Neroprotection | AHNAK, ASPH, CADM2, GATM, GRIK3, NRXN3, PCDH9, SPTBN1 +1 more | View in SCUBA |
| Pericytes | Pericyte ECM Secretion ECM production | CPM, CSRP2, DACH1, EFEMP1, FRZB, GULP1, MASP1, NDUFAF4 +3 more | View in SCUBA |
About the gene
| Synonyms | FHM2, MHP2 |
|---|---|
| Chromosome | 1: 160115759-160143591 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters |
| Molecular function | Translocase |
| Biological process | Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport |
Function
This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium, providing the energy for active transport of various nutrients
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.