SCUBA

PGM2L1 — Phosphoglucomutase 2 like 1

PGM2L1 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

PGM2L1's module in each cell type

Cell typeModuleShares the module with
CD4⁺ T cellsCD200 immunoregulation
Immune regulation
B3GNT2, CAV1, CD200, CD79A, CH25H, CHGB, DUOX1, ELF2 +23 moreView in SCUBA
Innate lymphoid cellsMitochondrial Metabolism
Mitochondrial & OxPhos
ACTR10, ANP32A, APOL3, ATP6V1E1, ECHS1, ERCC1, ETFB, GLRX3 +12 moreView in SCUBA

About the gene

SynonymsBM32A, FLJ32029
Chromosome11: 74330316-74398433
Predicted locationIntracellular
Essential geneNo
Protein classEnzymes, Metabolic proteins, Predicted intracellular proteins
Molecular functionIsomerase, Transferase
Biological processCarbohydrate metabolism, Glucose metabolism

Function

Glucose 1,6-bisphosphate synthase using 1,3- bisphosphoglycerate as a phosphate donor and a series of 1-phosphate sugars, including glucose 1-phosphate, mannose 1-phosphate, ribose 1- phosphate and deoxyribose 1-phosphate, as acceptors. In vitro, also exhibits very low phosphopentomutase and phosphoglucomutase activity which are most probably not physiologically relevant.

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.