PPP1R35 — Protein phosphatase 1 regulatory subunit 35
PPP1R35 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PPP1R35's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Mitochondrial Housekeeping Mitochondrial & OxPhos | ARL2, BRAT1, C11orf58, CCDC115, CD3E, CHMP4A, CHURC1, DPM3 +13 more | |
| Mucosal-associated invariant T cell | ER & Mitochondrial Assembly Protein processing & ER | ANAPC11, ARRDC1, ATP5MC1, COA3, CSTB, DECR1, GSTK1, HINT2 +9 more |
About the gene
| Synonyms | C7orf47, MGC22793 |
|---|---|
| Chromosome | 7: 100435282-100436497 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | Protein phosphatase inhibitor |
Function
During centriole duplication, plays a role in the centriole elongation by promoting the recruitment of the microtubule-binding elongation machinery through its interaction with RTTN, leading to the centriole to centrosome conversion. In addition, may play a role in the primary cilia assembly (By similarity).
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.