DPM3 — Dolichyl-phosphate mannosyltransferase subunit 3, regulatory
DPM3 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
DPM3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Mitochondrial Housekeeping Mitochondrial & OxPhos | ARL2, BRAT1, C11orf58, CCDC115, CD3E, CHMP4A, CHURC1, HAX1 +13 more | |
| Innate lymphoid cells | Mitochondrial Metabolic Housekeeping Mitochondrial & OxPhos | ALKBH7, ATF6B, BCAS1, COQ8A, DDT, DNAJC4, EIF3M, FDFT1 +16 more | View in SCUBA |
| Macrophages | ER Protein Glycosylation Vesicular traficking | AK2, ALG3, ALG5, BABAM1, CKLF, CRELD2, DDOST, FAM136A +21 more | View in SCUBA |
| Mucosal-associated invariant T cell | Mitochondrial Biogenesis Mitochondrial & OxPhos | ARFRP1, ARL2, ATP6V0E1, CALHM2, CCS, COA4, DBP, DENND2D +15 more |
About the gene
| Synonyms | MGC125904, MGC125905, MGC34275 |
|---|---|
| Chromosome | 1: 155139891-155140595 |
| Predicted location | Membrane |
| Essential gene | Yes |
| Protein class | Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Predicted membrane proteins |
Function
Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit DPM1 to the endoplasmic reticulum
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.