CHURC1 — Churchill domain containing 1
CHURC1 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CHURC1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Cytoskeletal Scaffolding Cytoskeletal | ADD1, AGPAT1, ANO6, ARL6IP5, CDC42BPA, DOCK1, ERC1, MAP4 +6 more | View in SCUBA |
| Gamma-delta T cells | Mitochondrial Housekeeping Mitochondrial & OxPhos | ARL2, BRAT1, C11orf58, CCDC115, CD3E, CHMP4A, DPM3, HAX1 +13 more | |
| Innate lymphoid cells | JAK-STAT Cytokine Signaling Inflammation | AASDHPPT, ARHGAP9, CIDEB, CSK, DCAF7, DENND2D, EDEM2, EIF4EBP2 +23 more | View in SCUBA |
| Lymphatic endothelial | Mitochondrial OxPhos Complex Mitochondrial & OxPhos | ARL2, BLOC1S1, CHMP2A, COX5B, DCTN3, FIS1, MRPL43, NDUFA11 +5 more | View in SCUBA |
| Mucosal-associated invariant T cell | Mitochondrial Metabolism & Redox Mitochondrial & OxPhos | ATP5PF, DAD1, DHRS7, EGLN2, HMOX2, ITM2B, MRPS21, NDUFS7 +7 more |
About the gene
| Synonyms | C14orf52, FLJ33064, My015 |
|---|---|
| Chromosome | 14: 64914361-64944591 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | Activator, Developmental protein |
| Biological process | Transcription, Transcription regulation |
Function
Transcriptional activator that mediates FGF signaling during neural development (By similarity). Plays a role in the regulation of cell movement (By similarity). Does not bind DNA by itself
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.