RETN — Resistin
RETN belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
RETN's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Macrophages | SPP1 Tissue Remodeling ECM remodeling | BST1, CD52, CHI3L1, CHIT1, CSF1, FBP1, FGR, FN1 +19 more | View in SCUBA |
| Monocytes | Multi-lineage Contamination Cell contamination | AZU1, CLU, CYP19A1, E2F2, ELANE, GM2A, GYPC, ITGB7 +4 more | View in SCUBA |
| Neutrophils | Immature Neutrophil Granule Developmental | BPI, CCDC85B, CD24, CEACAM8, CPNE3, OLFM4, RGCC, SVIP |
About the gene
| Synonyms | ADSF, FIZZ3, RETN1 |
|---|---|
| Chromosome | 19: 7669049-7670455 |
| Predicted location | Secreted |
| Essential gene | No |
| Protein class | Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins |
| Molecular function | Hormone |
Function
Hormone that seems to suppress insulin ability to stimulate glucose uptake into adipose cells (By similarity). Potentially links obesity to diabetes (By similarity). Promotes chemotaxis in myeloid cells.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.