CD52 — CD52 molecule

CD52 belongs to a gene co-expression module in 8 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

CD52's module in each cell type

Cell type	Module	Shares the module with
CD19⁺ B cells	MHC-II antigen presentation B cell maturation	ARID5A, CD74, CD79A, CTSS, CYBA, HLA-DPA1, HLA-DPB1, HLA-DQA1 +9 more	View in SCUBA
CD4⁺ T cells	Th17 lineage Th17 fate	ADA, ARHGEF3, CD226, DENND3, EVL, IDH2, IL17RE, IL23R +13 more	View in SCUBA
CD8⁺ T cells	Cytotoxic Effector cytotoxicity	APOBEC3H, B2M, CCL4, CCL5, CYBA, GZMH, HCST, HLA-A +4 more	View in SCUBA
Gamma-delta T cells	Effector Cell Migration migration & adhesion	ADAM15, ADAM8, ANXA2, APOBEC3G, CTSC, DSTN, FUT11, GLIPR2 +17 more
Hematopoietic progenitor cells	Quiescent HSC State Stemness	ARHGEF17, BAALC, BIN1, GNAI1, HOPX, MZB1, RBPMS, SPINK2
Innate lymphoid cells	ILC-1 identity Differentiation	ABRACL, BLOC1S1, C19orf53, DAD1, FUCA2, GMFG, HMGN3, ISCU +20 more	View in SCUBA
Macrophages	SPP1 Tissue Remodeling ECM remodeling	BST1, CHI3L1, CHIT1, CSF1, FBP1, FGR, FN1, GCHFR +19 more	View in SCUBA
Mucosal-associated invariant T cell	Cytoskeletal Remodeling Migration migration & adhesion	ADAM8, BIN2, C11orf21, CAPN1, CAPN2, CDC25B, CNN2, CYB561 +14 more

About the gene

Synonyms	CDW52, EDDM5, HE5
Chromosome	1: 26317958-26320523
Predicted location	Membrane
Essential gene	No
Protein class	Cancer-related genes, CD markers, FDA approved drug targets, Predicted membrane proteins

Function

May play a role in carrying and orienting carbohydrate, as well as having a more specific role

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.