SLC24A4 — Solute carrier family 24 member 4
SLC24A4 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SLC24A4's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Monocytes | CCR2+ Monocyte Identity Innate immunity | CCR2, GAPT, LYST, MAP3K1, MNDA, POU2F2, RGS18, TMEM154 +4 more | View in SCUBA |
About the gene
| Synonyms | NCKX4 |
|---|---|
| Chromosome | 14: 92322581-92501481 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters |
| Biological process | Antiport, Calcium transport, Ion transport, Olfaction, Potassium transport, Sensory transduction, Sodium transport, Symport, Transport |
Function
Calcium, potassium:sodium antiporter that transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+). Controls the rapid response termination and proper regulation of adaptation in olfactory sensory neurons (OSNs) which subsequently influences how odor information is encoded and perceived (By similarity). May play a role in calcium transport during amelogenesis.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.