SPEG — Striated muscle enriched protein kinase
SPEG belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SPEG's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | ICC contractility Gut motility | BEX1, BTC, DES, HACD1, HSPB7, IL17B, KCNMA1, LDB3 +7 more | View in SCUBA |
| Smooth muscle cells | Contractile Tone Regulation Contractility | ASPN, FAM13C, HAGH, HSPB6, PDE5A, PJA2, PRELP, RGS3 +2 more | View in SCUBA |
About the gene
| Synonyms | APEG1, BPEG, KIAA1297, MGC12676, MYLK6, SPEGalpha, SPEGbeta |
|---|---|
| Chromosome | 2: 219434843-219493629 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins |
| Molecular function | Kinase, Serine/threonine-protein kinase, Transferase |
| Biological process | Differentiation |
Function
Isoform 3 may have a role in regulating the growth and differentiation of arterial smooth muscle cells
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.