PRELP — Proline and arginine rich end leucine rich repeat protein
PRELP belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PRELP's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | Submucosal Fibroblast Developmental | ADAMTS19, ANGPTL7, C7, CHRDL1, DPT, GDF6, GPNMB, HAND2 +9 more | View in SCUBA |
| Glial cells | Neuroprotective Secretory Neroprotection | ANGPTL7, APCDD1, IGFBP6, LRRTM1, PDLIM2, SELENOP, TTR, TXNIP +1 more | View in SCUBA |
| Lymphatic endothelial | IL33 Alarmin Response Inflammation | CLIC4, EPAS1, HRCT1, IGFBP5, IL33, LIFR, PLAT, PLSCR1 +4 more | View in SCUBA |
| Smooth muscle cells | Contractile Tone Regulation Contractility | ASPN, FAM13C, HAGH, HSPB6, PDE5A, PJA2, RGS3, RNF150 +2 more | View in SCUBA |
About the gene
| Synonyms | prolargin, SLRR2A |
|---|---|
| Chromosome | 1: 203475806-203491352 |
| Predicted location | Secreted |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted secreted proteins |
| Molecular function | Heparin-binding |
Function
May anchor basement membranes to the underlying connective tissue
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.