STMP1 — Short transmembrane mitochondrial protein 1
STMP1 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
STMP1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Vesicular trafficking Housekeeping | ACSL4, ARL8B, BLOC1S2, C3orf38, DTX3L, EFCAB14, GGA2, HMGXB3 +17 more | View in SCUBA |
| Endothelial | ER Protein Processing Protein processing & ER | AP2S1, ATOX1, C1QBP, CCT3, DBI, ENO1, NHP2, OSTC +5 more | View in SCUBA |
| Gamma-delta T cells | Actin Remodeling Cytoskeletal | AP1M1, APOBEC3C, ATP5PB, CAP1, CAPN1, CAPZB, DBNL, LSP1 +10 more |
About the gene
| Synonyms | C7orf73, Mm47, PL-5283 |
|---|---|
| Chromosome | 7: 135662496-135693418 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Biological process | Immunity, Innate immunity |
Function
Microprotein involved in mitochondrial respiratory chain complex III (ubiquinol-cytochrome c oxidoreductase) and complex IV (mitochondrial cytochrome c oxidase complex) assembly. Required for the formation of mitochondrial supercomplexes (SCs). Also required for the activation of the NLRP3 inflammasome (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.