SCUBA

LSP1 — Lymphocyte specific protein 1

LSP1 belongs to a gene co-expression module in 10 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

LSP1's module in each cell type

Cell typeModuleShares the module with
CD19⁺ B cellsCytoskeleton/motility
migration & adhesion
ANXA2, ANXA4, BHLHE41, C4orf48, CAPG, CAPN2, CIB1, ISCU +11 moreView in SCUBA
CD4⁺ T cellsInterferon response
Anti-viral
ACTN4, CAPZA1, CHMP4A, CHMP5, EFHD2, IL12RB1, PARP14, PIN1 +7 moreView in SCUBA
CD8⁺ T cellsActin Cytoskeleton
Cytoskeletal
ACTB, ARF6, ARPC1B, ARPC4, BRK1, CAPZB, CFL1, CORO1A +10 moreView in SCUBA
FibroblastsQuiescent Anti-inflammatory Fibroblast
Developmental
ADIRF, CHCHD10, DACH1, FXYD6, IGFBP3, KHDRBS3, NDRG2, PDE1A +3 moreView in SCUBA
Gamma-delta T cellsActin Remodeling
Cytoskeletal
AP1M1, APOBEC3C, ATP5PB, CAP1, CAPN1, CAPZB, DBNL, PIH1D1 +10 more
Hematopoietic progenitor cellsLymphocyte Signaling
Lymphcyte development
ADGRG5, AHR, AKNA, CARD11, CORO1A, CYTH4, KIAA0930, PAK1 +3 more
Innate lymphoid cellsMitochondrial OxPhos
Mitochondrial & OxPhos
AKR7A2, ANXA6, AP2M1, ARL6IP4, ARPC1B, ATP5MC2, ATP5PB, BSG +21 moreView in SCUBA
Mucosal-associated invariant T cellCyclophilin-Mediated Folding
Housekeeping
B2M, BBLN, BCL7C, C12orf75, CFL1, EDF1, EIF3L, ERH +10 more
Natural Killer cellsResident NK cells
Gut residency
ANXA11, APBB1IP, CD151, CXXC5, HMOX2, MPG, PPDPF, SH3BP1 +4 moreView in SCUBA
NeutrophilsNeutrophil Motility Cytoskeleton
Migration & adhesion
CDKN2D, CNN2, COTL1, CST7, GLIPR1, GMFG, GNB2, GPSM3 +9 more

About the gene

SynonymsWP34
Chromosome11: 1850904-1892267
Predicted locationIntracellular
Essential geneNo
Protein classPredicted intracellular proteins

Function

May play a role in mediating neutrophil activation and chemotaxis

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.