STXBP5 — Syntaxin binding protein 5
STXBP5 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
STXBP5's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Enterocytes | Cortical actin junctions Cytoskeletal | GOLGB1, JAK2, MYO1B, NEBL, PKP4, TTC39B | View in SCUBA |
About the gene
| Synonyms | LLGL3, tomosyn, tomosyn-1 |
|---|---|
| Chromosome | 6: 147204180-147391010 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Biological process | Exocytosis, Protein transport, Transport |
Function
Plays a regulatory role in calcium-dependent exocytosis and neurotransmitter release. Inhibits membrane fusion between transport vesicles and the plasma membrane. May modulate the assembly of trans- SNARE complexes between transport vesicles and the plasma membrane. Inhibits translocation of GLUT4 from intracellular vesicles to the plasma membrane. Competes with STXBP1 for STX1 binding (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.