TTC39B — Tetratricopeptide repeat domain 39B
TTC39B belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TTC39B's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Enterocytes | Cortical actin junctions Cytoskeletal | GOLGB1, JAK2, MYO1B, NEBL, PKP4, STXBP5 | View in SCUBA |
About the gene
| Synonyms | C9orf52, FLJ33868 |
|---|---|
| Chromosome | 9: 15163622-15307360 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted membrane proteins |
| Biological process | Lipid metabolism, Ubl conjugation pathway |
Function
Regulates high density lipoprotein (HDL) cholesterol metabolism by promoting the ubiquitination and degradation of the oxysterols receptors LXR (NR1H2 and NR1H3)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.